Hence persons of blood group O are also called Universal Donors. Group O blood has neither A and B Antigens, so this blood can be given to anyone. So it is very important in blood transfusion that only that blood group is infused whose red cell do not carry an Antigen which be attacked by his own Antibodies. This makes the donated red cells stick together or Agglutinate, which can be fatal. For example if a person of blood group A is given blood from a donor with blood group B, his anti B Antibodies will stick to the B Antigens on the ‘imported’ red blood cells entering his body. The respective Antibodies are Anti B, Anti A, None and Anti A & Anti B.ĭuring Transfusions Blood Matching has to be done. For example, Blood Groups A, B, AB and O have Antigens A, B, A&B and None respectively. The antibodies in a human's blood plasma are always the opposite of the antigens on the RBCs. Antibody or Anti A acts against antigen A. If a person has both antigens, he is group AB and if he has neither, the blood group is O.Īntibodies against these two Antigens are found in the blood Plasma. Antigen B makes a person's Blood group B. A person has either one or both or neither on the RBCs.Ī person with Blood Group A is so because he has antigen A. The two especially important antigens called A and B. ![]() A Human's Red blood cells (RBCs) have a set of Antigens on them.
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